Details of medicinal aluminum collapsible tubes

Aluminum hose as the basis for ointment tube

1. What is aluminum hose

2. The historical origin of medicinal aluminum collapsible tube ointment

Third, why use aluminum hose as medicinal ointment tube

Four, summary

1. What is aluminum hose?

Aluminum hose, also known as aluminum hose, aluminum collapsible tube hose, pure aluminum hose. The aluminum hose is stamped from 99.7% pure aluminum ingots.

Aluminum hoses need to go through the process of nozzle thread trimming, nozzle and tail trimming, annealing softening, internal spraying, tail coating and tail sealing, primer coating, thin top sealing film, appearance printing and other processes to form aluminum packaging hoses. It can be used for filling cosmetic creams, toothpastes, ointments, ointments, and food sauces. It is a small packaging material for household products.



2. The origin of aluminum hose as ointment tube

The production and application of ointment tubes and the replacements that have gone through three generations are lead-tin hoses; aluminum hoses without inner coating and tail coating; the ones on the market today that have undergone inner coating, thin top sealing film, printing and tail coating , The third-generation medical aluminum hose that continues to be used today.

The first generation is the predecessor of the aluminum hose is the lead tin hose. Lead can cause serious harm to the human body, and tin resources are less, so it has long been eliminated by the market.

The second generation is an aluminum hose that has not been treated inside the tube. Due to the poor sealing, this kind of product cannot isolate the drug from the air. The exposed aluminum material and the drug are prone to chemical reactions, which directly involve the safety of the drug. Therefore, such products are gradually eliminated in the packaging market.

The third generation is the aluminum hose currently on the market. The State Food and Drug Administration made specifications for aluminum pharmaceutical ointment tube YB00162002-2015. Aluminum hoses must have inner coating, thin top sealing film, printing and tail coating, and tail sealing. The technical level of medical aluminum hoses is essentially different and improved from the second-generation products. With a thin top sealing film and a sealing coating at the tail, it can ensure that the medicine does not come into contact with the air during the storage period, and does not cause leakage or drying up. The inner wall coating of the aluminum collapsible tube effectively isolates the drug from direct contact with the aluminum collapsible tube, providing a guarantee for the efficacy and safety of the drug during the validity period; the multi-color printing technology makes the appearance more beautiful.

uploading...

3. Why use aluminum hose as ointment tube?

Why use aluminum hose as a medicinal hose, and what are the benefits of using aluminum hose for ointment?

1) Ointment tubes include plastic ointment tubes, aluminum-plastic composite ointment tubes, and aluminum pharmaceutical ointment tubes.

2) Aluminum materials have airtightness and anti-corrosion properties, which can improve the shelf life of medicines, while plastic packaging has a larger permeability coefficient to oxygen and carbon monoxide. Most drugs are easy to be oxidized, decomposed, deteriorated, and light-resistant, while the surface of aluminum and its alloys is easy to form a dense oxide protective film, which can effectively isolate water vapor, oxygen, etc., and avoid product circulation and use It is corroded during the process; and the aluminum packaging with tail glue has better sealing characteristics, and can have a more adequate sealing protection effect on the medicines inside.

3) Aluminum materials have strong barrier properties, and plastic products are generally organic materials, which are easy to age. Ointment packaging has strict requirements for sealing. Aluminum has excellent moisture and gas barrier properties, and has gas impermeability. Aluminum hoses are used as ointment packaging to protect the ointment.

4) Aluminum-plastic tubes and plastic medical hoses are easy to chemically react with ointments with poor chemical properties. Although they are easy to carry and have a price advantage, they are easy to chemically react with ointments that are chemically stable and affect the effectiveness of the ointment.

5) The aluminum hose is squeezable and has no rebound characteristics. Aluminum-plastic composite pipes are widely used in the daily chemical industry because of their beautiful appearance. But for medicine packaging, the aluminum-plastic composite tube has obvious shortcomings relative to the special requirements of medicines. In addition to environmental protection reasons, the aluminum-plastic composite pipe has not been able to solve the problem of 'rebound' and the ingress of outside air. The entire process of pharmaceutical packaging materials and pharmaceutical production and filling is completed in a clean environment, which requires very high hygiene and safety. However, a large amount of unpurified outside air generated by the 'rebound' phenomenon of the composite tube enters the tube to directly contact the drugs, and secondary pollution of the drugs may occur.


Four, summary

1) The aluminum-plastic tube and the plastic medical tube are easy to carry and have a price advantage, but they are easy to chemically react with the chemically stable ointment, which affects the effectiveness of the ointment;

2) The plastic packaging of ointment will accelerate the aging and deterioration of medicines, reduce the shelf life, etc., and the drug management agencies of various countries are very cautious in the selection of plastic packaging materials;

3) In recent years, the production technology of medicinal aluminum hoses has been continuously developed, and aluminum collapsible tubes with plastic cleaning heads and sharp-mouth ointment tubes with cleaning heads have been developed. It can avoid the aluminum blackening caused by the friction of the threaded mouth, and effectively improve the cleanliness of the medicine and the safety of the medicine.

The national pharmaceutical industry continues to be marketized and internationalized. Medical aluminum hose products can be closer to the needs of consumers, and the pharmaceutical aluminum hose packaging industry will have a broad market space.