Plastic squeezable tube filling and sealing technique for medicine

The soft tube filling and sealing standard specifies the model, type and basic parameters, technical requirements, test methods, inspection rules and marks, packaging, transportation and storage requirements of the soft tube filling and sealing machine. It is suitable for the soft tube filling and sealing machine which is widely used in paste products of many industries. What do all parties think of the new standards? What direction will soft tube filling and sealing technology develop? This article, This article from Cosmetic Tube Manufacturer, hopes to be enlightening to readers of the medical packaging technology forum. The content of the standard to be reviewed is summarized. The main content of the standard project involves the subject. The model of the sealing machine is prepared by GB/T The specified form of 7311 degree of automation semi-automatic, automatic tail sealing mode internal heat, flanged filling valve number single head, multiple head basic parameters filling precision filling quantity ml filling precision error % soft tube diameter mm Max soft tube length mm≥5 ~ 60±210 ~ 40180 > 60 ~ 500±120 ~ 60300 soft tube pattern No scratches, no irregularities, no leakage, no cauterization and pressure penetration. Clear print date Filling accuracy Qualification rate is not less than 98% Packaging Qualification rate is not less than 98% Tail-sealing machine noise is not more than 80dB(A) Safety protection should conform to JB 7233, GB 2894 and GB The provisions of the 16179 experimental method empty running test, precision and accuracy test, capacity test, filling percent of pass test work, packaging, percent of pass test, noise test, electrical safety testing, safety inspection, the appearance quality inspection, and so on detection rules slightly logo, packaging, transport and storage slightly the national packaging machinery branch of standardization technical committee Background and significance of standard formulation: domestic soft tube filling and sealing machine suppliers are mainly based on the introduction and absorption of foreign advanced technology, according to the domestic characteristics of research and development. Machinery production enterprises in the development of enterprise standards can not find the reference basis, they require to have industry standards to guide production; At the same time, the use of the industry is more concerned about the development of this standard, machine users and local quality supervision departments urgently need to introduce the industry standard as soon as possible to measure the quality of this kind of equipment.

On the one hand, the standard of "Soft Tube Filling and Sealing Machine" will benefit the machinery production enterprises. It can be used as the standard to guide the production of the whole industry and promote the healthy and benign development of the industry. On the other hand, the standard can serve as the basis that each quality supervises branch and broad consumer measure product quality. In summary, the starting point of the standard is to meet the industry's need for standards. Since there is no national and industrial standard for the soft tube filling and sealing machine in China before, we will develop the standard through the market survey of the soft tube filling and sealing machine industry and the performance test data of the product, so as to make the standard reach the advanced level in China. Discussion on Standard and Technology of Soft Tube Filling and Sealing by Pharmaceutical Enterprises

The establishment of the standard of soft tube filling and sealing machine plays a very important role for pharmaceutical production enterprises. On the one hand, when pharmaceutical enterprises accept the equipment, they can measure whether the machine meets the specification according to the standard, and select the high-quality soft tube filling and sealing equipment according to the standard. On the other hand, in the maintenance and repair of equipment, we can take the standard as a reference, analyze and master the condition of the equipment, and take targeted maintenance measures; At the same time, after the standard, the specific reference data is more convenient for the certification of pharmaceutical enterprises. Mr. Li Wenxiang: The forthcoming standard of soft tube filling and sealing machine will certainly play a normative role in the industry. Especially for the national enterprises have a positive direction, can improve and standardize the equipment market, the formation of survival of the fittest, ensure the healthy and orderly development of national enterprises; For user enterprises, the basic performance of the equipment can be guaranteed to maintain long-term stability; Combining with the GMP standard that pharmaceutical enterprises attach most importance to, it can assist the implementation of GMP and also meet the SFDA tube regulation for pharmaceutical enterprises. Expect the development of soft tube filling and sealing technology

One of the issues most relevant to pharmaceutical companies in the Standard for Soft Tube Filling and Sealing Machinery is the accuracy of filling. If the error is slightly large, pharmaceutical enterprises have to increase the filling volume to avoid the problem of insufficient filling weight. Therefore, we believe that under the new standard, the soft tube filling and sealing equipment is bound to develop towards the direction of high precision. The ointment medicines produced by our company adopt three-layer edge folding and end sealing. Therefore, we hope that the filling and end sealing machine can make the soft tube more uniform in width, less inclined, beautiful and durable in edge folding. First of all, the soft tube filling and sealing machine needs to get rid of the low productivity and increase the speed to create higher production efficiency. Secondly, the configuration of the equipment should be gradually improved. The cleaning system, overload system, especially the selection system of the detection system are few, and the current situation of excessive volume needs to be further improved. At the same time, the processing of filling valve should be further improved; Finally, the safety system of the equipment itself is expected to be more perfect. Once the equipment stops operating, some details are expected to be processed to protect the motor. Mr. Li Li: The soft tube filling and sealing machine belongs to the hardware. In order to give full play to its advantages, the corresponding software is also needed. This includes a comprehensive package of maintenance, repair, and tube handling, supported by a highly qualified staff. For the specific situation of the equipment, it is necessary to formulate targeted system in line with the situation, and establish an excellent equipment tube system.

In order to ensure the maximum production efficiency of the filling and sealing equipment, we fully pay attention to the following points when using it:

1. Check the wear and tear of the filling system and replace damaged sealing rings at each batch replacement;

2. Clean up material traces on tube device, filling device and folding device;

Cleaning the lens of the positioning photoelectric detection device, etc.

Machinery manufacturing enterprises are often based on their own experience to refer to foreign machinery to do, the lack of corresponding theoretical guidance. However, only with unique performance can products better open the market, so mechanical manufacturers often have to continue to research and development to join the part of independent design, to improve the content of science and technology and practicality of products. The upcoming machinery standards guide the direction of the booming industry, the machinery production enterprises to close to the standard, in order to continue to hit a new high. Mr. Huang Xuanrong: We welcome the introduction of the "Soft Tube Filling and Sealing Machine" standard by the Mechanical Standards Committee. At present, the competition among domestic soft tube filling machine enterprises is fierce and the price is chaotic. After the introduction of new standards, the industry can be standardized to promote the better development of the technology. At present, the GMP certification of the pharmaceutical industry has ended, is about to face a new round of cGMP certification, in this stage, the introduction of this standard for pharmaceutical enterprises or suppliers have a good guiding role. Development direction of soft tube filling and sealing technology

First, the filling and sealing speed of aluminum tube for the former domestic single-head equipment is 60-80tube/ min, plastic tube is 40-50tube/ min, and the speed of double-head equipment is 120-160tube/ min. This is still far from the international high speed production line. The development towards high speed is a trend of soft tube filling and sealing machine. Our company has developed a new second generation of elliptical conveying single head machinery, speed can be increased by about 40%, the number of stations increased from 9 to 18.

2. Intelligent machinery with high automation will be easier to operate and control. Foreign advanced equipment has adopted robots to complete tube up, tube out and other processes. Mr. Huang Xuanrong: Due to the high price of pharmaceutical products, the requirements for product safety are high, and the requirements for filling accuracy and sealing quality are higher than other industries. In the future, the development direction of soft tube filling technology is mainly as follows: First, to meet the needs of large enterprises to improve production efficiency; Second, it doesn't take much time for SMEs to change to a different product specification to satisfy a small amount of diversification. Our company adopts a new generation of rapid disassembly nozzle system and die base, do not need tools can be cleaned and disinfected, more can improve the production efficiency. How to choose the right soft tube filling and sealing machine

When pharmaceutical enterprises choose equipment, firstly, they should match the most suitable filling and sealing equipment with high stability and safety according to the production capacity of the existing production line. Second, for enterprises with small product output and many specifications, we must pay attention to whether the operation and adjustment of replacement specifications are convenient and time-saving; Third, the equipment needs to be maintained and repaired, whether the replacement of parts is convenient, whether the after-sales service is in place, these are the important factors that pharmaceutical enterprises pay attention to when buying equipment. Mr. Huang Xuanrong: The key point of soft tube filling and sealing machine selection is the filling accuracy of the equipment, the strength and beauty of the sealing, and the safety of the equipment. Taiwan has fully implemented the pharmaceutical industry cGMP, our company has considerable experience. Tube pressure testing machine can test whether the sealing strength is up to production standards; In terms of safety, the setting of the safety door can make the equipment stop automatically when the personnel open the safety door on the way of operation. Of course, more attention should be paid to the education and training of workshop personnel and after-sales service, whether the manufacturer's spare parts are sufficient, etc. Mr. Tan Guolin: In the medical field, the requirements for soft tube filling and sealing technology are getting higher and higher, which can be seen from the development of industry standards. There are special departments abroad to test the safety of equipment. Safety includes the safety of the operation and the safety of the equipment itself, which is increasingly valued in China. With the development of technology, the price factor should also be fully considered. Research on some products to reduce the cost can better meet the needs of users.

Mr. Zhu, Manager of Equipment Department of Lianyungang Zhongjin Pharmaceutical Packing Co., Ltd., said: At present, the filling and sealing machinery industry in China is relatively prosperous. The standard can further standardize the industry, which will be helpful to ensure the stable quality of products. The pharmaceutical industry has the highest requirements for safety among all industries, and the sealing properties specified in the Soft Tube Filling and Sealing Machinery Standard are most closely related to the soft tube industry. How to ensure the sealing of the soft tube: our company has plastic soft tube, aluminum plastic composite soft tube, plastic plastic composite soft tube three categories of soft tube products. At present, the soft tube of PE inner lining is commonly used for medical use, and the sealing performance can be guaranteed from the soft tube itself. In order to ensure the quality of the soft tube, we pay great attention to the improvement of the laminating process to avoid the problem of insufficient sealing or delamination. In addition, the user in the sealing compound method of use is also related to the sealing of medical cream products. Directions for Soft-Tube: Soft-Tube will evolve in three directions: a greater emphasis on the use of environmentally friendly materials; Transparent soft tube for easy and intuitive display of content; Easy to print. Postscript The forthcoming introduction of the standard "Soft Tube Filling and Sealing Machine" has brought good news to the packaging of ointment products. At present, there is still a certain gap between the domestic soft tube filling and sealing machinery and the international level. The establishment of this standard is the beginning of shortening the gap between us and the international advanced level. From now on, the soft tube filling and sealing technology will develop in the direction of higher speed and higher automation under the guidance of standards. When pharmaceutical enterprises choose soft tube filling and sealing equipment, they must take the new standard as a reference to make the equipment become a competitive tool for pharmaceutical enterprises!